L pmid list csv create file 1 selected item: 17969000 format summary summary (text) abstract abstract (text) medline xml pmid list mesh and other data e-mail subject additional text e-mail "spam" filtering software notice add to clipboard add to collections order articles add to my bibliography generate a file for use with external citation management software. Create file sorry, your browser is unsupported so ncbi web applications may not function properly. More information. Pediatr pulmonol. 2007 dec;42(12):1207-14. Lung disease in niemann-pick disease. Guillemot n, troadec c, de villemeur tb, clã©ment a, fauroux b. Source ap-hp, hopital armand trousseau, pediatric pulmonary department, paris, france. Abstract background: lung involvement in children with niemann-pick disease has rarely been studied systematically. Objective: to assess the involvement of the lung and the value of bronchoalveolar lavage in children with niemann-pick diseases. Design: retrospective analysis of patient records. Patients: thirteen patients, with type a (n = 1), type b (n = 10), and type c (n = 2) niemann-pick disease, aged 2 months to 9 years at diagnosis, were included in the study. viagra buy buy generic viagra cheap viagra online viagra online cheap generic viagra viagra online viagra cheap pills cheap viagra online buy cheap viagra cheap generic viagra Interventions: lung involvement was assessed by clinical evaluation, chest radiograph, lung computed tomography (ct) scan, pulmonary function tests, and bronchoalveolar lavage fluid analysis. Results: respiratory symptoms were present at diagnosis in 10 patients and developed during follow up in the three other patients. All patients showed signs of interstitial lung disease on chest x-ray and lung ct scan. Bronchoalveolar lavage fluid analysis (n = 7) revealed a marked accumulation of foamy macrophages (niemann-pick cells) in all patients. At follow up, one patient died of respiratory failure, five patients required long term oxygen therapy and seven other patients presented a chronic obstructive pulmonary disease (n = 6) or chronic cough (n = 1). Conclusion: lung disease was observed in all the patients included in the present study. Bronchoalveolar lavage may be useful in niemann-pick diseases by showing the presence of characteristic niemann-pick cells. Pmid: 17969000 [pubmed - indexed for medline] mesh terms mesh terms biopsy bronchoalveolar lavage bronchoalveolar lavage fluid/cytology child.
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